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Natural Products as α-Amylase and α-Glucosidase Inhibitors and their Hypoglycaemic Potential in the Treatment of Diabetes: An Update

JOURNAL ARTICLE published 1 April 2010 in Mini-Reviews in Medicinal Chemistry

Authors: R. Tundis | M.R. Loizzo | F. Menichini

https://doi.org/10.2174/138955710791331007 Actions

Structure–activity relationships of pancreatic α-amylase and α-glucosidase as antidiabetic targets

BOOK CHAPTER published 2021 in Bioactive Natural Products

Authors: Prasad Dandekar | Sudha Ramkumar | Ameeta RaviKumar

https://doi.org/10.1016/b978-0-12-819489-8.00014-4 Actions

2-Hydroxyquinoline and Its Structural Analogs Show Antidiabetic Effects against α-Amylase and α-Glucosidase

JOURNAL ARTICLE published 31 March 2015 in Journal of Applied Biological Chemistry

Authors: Hwa-Won Lee | Hoi-Seon Lee

https://doi.org/10.3839/jabc.2015.001 Actions

Antidiabetic potential and enzyme kinetics of benzothiazole derivatives and their non-bonded interactions with α-glucosidase and α-amylase

JOURNAL ARTICLE published April 2016 in Medicinal Chemistry Research

Authors: Ninad V. Puranik | Hemalata M. Puntambekar | Pratibha Srivastava

https://doi.org/10.1007/s00044-016-1520-3 Actions

Evaluation of In Vitro α‐Amylase and α‐Glucosidase Inhibitory Potentials of 14 Medicinal Plants Constituted in Thai Folk Antidiabetic Formularies

JOURNAL ARTICLE published April 2018 in Chemistry & Biodiversity

Research funded by Prince of Songkla University (TTM560523S‐012130)

Authors: Chonlatid Somtimuang | Opeyemi Joshua Olatunji | Chitchamai Ovatlarnporn

https://doi.org/10.1002/cbdv.201800025 Actions

Design and synthesis of new antidiabetic α-glucosidase and α-amylase inhibitors based on pyrimidine-fused heterocycles

JOURNAL ARTICLE published July 2015 in Medicinal Chemistry Research

Research funded by Iran National Science Foundation (92001695,88001894)

Authors: Sara Shahidpour | Farhad Panahi | Reza Yousefi | Maryam Nourisefat | Marzieh Nabipoor | Ali Khalafi-Nezhad

https://doi.org/10.1007/s00044-015-1356-2 Actions

Multicomponent reaction for the synthesis of new 1,3,4-thiadiazole-thiazolidine-4-one molecular hybrids as promising antidiabetic agents through α-glucosidase and α-amylase inhibition

JOURNAL ARTICLE published October 2021 in Bioorganic Chemistry

Authors: Lalitha Gummidi | Nagaraju Kerru | Oluwakemi Ebenezer | Paul Awolade | Olakunle Sanni | Md. Shahidul Islam | Parvesh Singh

https://doi.org/10.1016/j.bioorg.2021.105210 Actions

Synthesis and Potential Antidiabetic Properties of Curcumin-Based Derivatives: An In Vitro and In Silico Study of α-Glucosidase and α-Amylase Inhibition

JOURNAL ARTICLE published January 2023 in Medicinal Chemistry

Research funded by Research Council of Kermanshah University of Medical Sciences (990347)

Authors: Hadi Adibi | Reza Khodarahmi | Mohammad Ezati | Fahimeh Ghavamipour | Narges Khosravi | Reza H. Sajedi | Maryam Chalabi | Alireza Farokhi

https://doi.org/10.2174/1573406418666220509101854 Actions

Lupane Analogue from Bark of Pithecellobium dulce and in vitro α-Glucosidase and α-Amylase Enzyme Inhibition Assay of Extract for Potential Antidiabetic Activity

JOURNAL ARTICLE published March 2016 in Chemistry of Natural Compounds

Authors: Shankar D. Katekhaye | Atish Paul | K. S. Laddha

https://doi.org/10.1007/s10600-016-1645-0 Actions

Antidiabetic Effect of Polyphenolic Extracts from Selected Edible Plants as α-Amylase, α -Glucosidase and PTP1B Inhibitors, and β Pancreatic Cells Cytoprotective Agents - A Comparative Study

JOURNAL ARTICLE published 21 August 2015 in Current Topics in Medicinal Chemistry

Authors: Małgorzata Zakłos-Szyda | Iwona Majewska | Małgorzata Redzynia | Maria Koziołkiewicz

https://doi.org/10.2174/1568026615666150619143051 Actions

Natural Prenylchalconaringenins and Prenylnaringenins as Antidiabetic Agents: α-Glucosidase and α-Amylase Inhibition and in Vivo Antihyperglycemic and Antihyperlipidemic Effects

JOURNAL ARTICLE published 1 March 2017 in Journal of Agricultural and Food Chemistry

Research funded by National Natural Science Foundation of China (21502138) | Laboratory Innovation Foundation of Undergraduate of Tianjin University of Science & Technology (1504A301) | Scientific Research Foundation of Tianjin University of Science & Technology (20110115)

Authors: Hua Sun | Dong Wang | Xiaotong Song | Yazhou Zhang | Weina Ding | Xiaolin Peng | Xiaoting Zhang | Yashan Li | Ying Ma | Runling Wang | Peng Yu

https://doi.org/10.1021/acs.jafc.6b05445 Actions

Inhibitory effects of chickpea and Tribulus terrestris on lipase, α-amylase and α-glucosidase

JOURNAL ARTICLE published August 2016 in Food Chemistry

Authors: Pınar Ercan | Sedef Nehir El

https://doi.org/10.1016/j.foodchem.2016.03.012 Actions

Design, synthesis and antidiabetic study of triazole clubbed indole derivatives as α-glucosidase inhibitors

JOURNAL ARTICLE published October 2023 in Bioorganic Chemistry

Authors: Priyanka Sharma | G.D. Gupta | Vivek Asati

https://doi.org/10.1016/j.bioorg.2023.106750 Actions

α-Glucosidase and α-amylase inhibitory activities of guava leaves

JOURNAL ARTICLE published November 2010 in Food Chemistry

Authors: Hui Wang | Yang-Ji Du | Hua-Can Song

https://doi.org/10.1016/j.foodchem.2010.03.088 Actions

Routine α-Amylase Assay Using Protected 4-Nitrophenyl-1,4-α-d-maltoheptaoside and a Novel α-Glucosidase

JOURNAL ARTICLE published 1 May 2000 in Clinical Chemistry

Authors: Klaus Lorentz

https://doi.org/10.1093/clinchem/46.5.644 Actions

Apigenin analogs as α-glucosidase inhibitors with antidiabetic activity

JOURNAL ARTICLE published February 2024 in Bioorganic Chemistry

Research funded by Natural Science Foundation of Hubei Province (2023AFB106)

Authors: Honghui Liu | Puxin Huang | Xingchen Wang | Yufang Ma | Jing Tong | Jing Li | Hong Ding

https://doi.org/10.1016/j.bioorg.2023.107059 Actions

Structural requirements of flavonoids for the selective inhibition of α-amylase versus α-glucosidase

JOURNAL ARTICLE published February 2022 in Food Chemistry

Authors: Jongbin Lim | Mario G. Ferruzzi | Bruce R. Hamaker

https://doi.org/10.1016/j.foodchem.2021.130981 Actions

Hypoglycaemic effect of comatin, an antidiabetic substance separated from Coprinus comatus broth, on alloxan-induced-diabetic rats

JOURNAL ARTICLE published July 2010 in Food Chemistry

Authors: Zhongyang Ding | Yingjian Lu | Zhaoxin Lu | Fengxia Lv | Yuhong Wang | Xiaomei Bie | Feng Wang | Kechang Zhang

https://doi.org/10.1016/j.foodchem.2009.12.001 Actions

A Prospect for Pyrrolidine Iminosugars as Antidiabetic α-Glucosidase Inhibitors

JOURNAL ARTICLE published 13 December 2012 in Journal of Medicinal Chemistry

Authors: Ana Trapero | Amadeu Llebaria

https://doi.org/10.1021/jm301682r Actions

Multifunctional isoxazolidine derivatives as α-amylase and α-glucosidase inhibitors

JOURNAL ARTICLE published May 2020 in Bioorganic Chemistry

Authors: Ameni Ghabi | Jihed Brahmi | Fahad Alminderej | Sabri Messaoudi | Sébastien Vidal | Adel Kadri | Kaïss Aouadi

https://doi.org/10.1016/j.bioorg.2020.103713 Actions
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